OECD HPV Dossiers

In 1998, the global chemical industry, led by the International Council of Chemical Associations (ICCA), set itself the goal of providing data and initial hazard assessments to the Organisation for Economic Co-operation and Development (OECD) for approximately 1,000 High Production Volume (HPV) chemicals produced at > 1,000 mt/y, that represent more than 90 % of global chemicals production

The information gathered consists of a Screening Information Data Set (SIDS) Dossier, which is a basic set of health and environment data required for making an initial hazard assessment of HPV chemicals by the member countries of the OECD. SIDS data are used to "screen" the chemicals and set priorities for further testing or risk assessment.

The HPV programme was facing several challenges. The demands placed on company resources by REACH, the European chemicals legislation, had limited industry's ability in the EU and outside to move more rapidly on its HPV commitments. In 2014 the OECD stopped sponsoring the HPV programme, and started the OECD Cooperative Chemicals Assessment Programme (CoCAP)to better respond to the changing needs of member countries; it addresses a number of member country challenges, such as dealing with more chemicals in a shorter period of time, addressing all chemicals on the market, and avoiding duplication of on-going work in other countries.


ECSA was committed to lead the HPV initiative for their substances and actively supported the Swiss authorities in preparing high quality SIDS dossiers for Methylene Chloride and Carbon Tetrachloride. The conclusions were agreed by the OECD in 2011, and SIAPs (SIDS Initial Assessment Profile) & SIARs (SIDS Initial Assessment Report) prepared; the SIAPs can be retrieved on the public OECD Existing Chemicals Database website.

Last update: 02/2018