OECD HPV Dossiers

In 1998, the global chemical industry, led by the International Council of Chemical Associations (ICCA), set itself the goal of providing data and initial hazard assessments to the Organisation for Economic Co-operation and Development (OECD) for approximately 1,000 High Production Volume (HPV) chemicals produced at > 1,000 mt/y, that represent more than 90 % of global chemicals production

The information gathered consists of a Screening Information Data Set (SIDS) Dossier, which is a basic set of health and environment data required for making an initial hazard assessment of HPV chemicals by the member countries of the OECD. SIDS data are used to "screen" the chemicals and set priorities for further testing or risk assessment.

The HPV programme was facing several challenges. The demands placed on company resources by REACH, the European chemicals legislation, had limited industry's ability in the EU and outside to move more rapidly on its HPV commitments. In 2014 the OECD stopped sponsoring the HPV programme, and started the OECD Cooperative Chemicals Assessment Programme (CoCAP)to better respond to the changing needs of member countries; it addresses a number of member country challenges, such as dealing with more chemicals in a shorter period of time, addressing all chemicals on the market, and avoiding duplication of on-going work in other countries.


ECSA was committed to lead the HPV initiative for their substances and actively supported the Swiss authorities in preparing high quality SIDS dossiers for Methylene Chloride and Carbon Tetrachloride. The conclusions were agreed by the OECD in 2011, and SIAPs (SIDS Initial Assessment Profile) & SIARs (SIDS Initial Assessment Report) prepared; the SIAPs can be retrieved on the public OECD Existing Chemicals Database website.

Last update: 02/2018

Montreal Protocol Meeting - ECSA & HSIA side event

November 2017

DCM & the ozone layer
24 November 2017 – 13hrs – Montréal

During this side event, we will provide you with scientific facts and figures on the worldwide production, emissions of the VSLS Dichloromethane (DCM) and its negligible contribution to ozone depletion.
We will consider the following criteria: global production by industry and emissions, global natural production, behavior and effect on the atmosphere, regulatory overview for DCM. The full paper is available here. A one-pager summary is also available.
More information

IOELVs for DCM, CTC and PER published

February 2017

Indicative Occupational Exposure Limit Values (IOELVs) for DCM, CTC and PER have been published by the EU Commission (cf. DIRECTIVE (EU) 2017/164 of 31.1.2017), which are in line with the REACH DNEL(inhalation) for workers. 
These IOELVs have to be considered by member states for setting national exposure limits (OELs), which they have to accomplish by 21. August 2018. Only national OELs are legally binding for occupational safety, whereas the IOELVs have to be considered by users in case no OELs is set, yet.  The relevant OELs are provided with the SDS of the solvents suppliers (cf. chapter 8.1). 


UBA PMT criteria published

February 2018

The German Environment Agency (UBA, Umweltbundesamt) has published the assessment of "Persistence, Mobility and Toxicity (PMT)" with the desire to protect drinking water sources. Applying conservative criteria for PMT as defined by UBA, perchloroethylene (PER) and trichloroethylene (TRI) appear as number 2 and 3 on the report. UBA also aims to establish PMT as an equivalent concern to identify SVHC substance for authorisation under REACH. ECSA does not consider SVHC identification using PMT criteria as the appropriate tool to improve drinking water quality due to this being a pure hazard based approach and thus does not consider risk. TRI is already listed in Annex XIV (authorisation) and today PER is handled almost exclusively in closed systems with no intentional emission to water or soil. For further information see the ECSA position paper on PER here.

New Study on DCM

October 2016

Together with HSIA, ECSA supported a study to clarify the mode of action of cancer formation for methylene chloride (DCM). A publication is expected soon in a peer reviewed scientific journal. The outcome of the study shows that below a threshold there is no risk on cancer formation related to DCM.